One-Stage Anterior Approach for Four-Vessel Occlusion in Rat
نویسندگان
چکیده
منابع مشابه
One-stage anterior approach for four-vessel occlusion in rat.
BACKGROUND AND PURPOSE We report a modified 4-vessel occlusion (4VO) rat model. METHOD We used a 1-stage anterior approach for making bilateral hemispheric ischemia. RESULTS Modified 4VO method decreased cerebral blood flow to 12% to 14% of baseline levels. CONCLUSIONS This modified 4VO method is a minimally invasive, quick, reliable procedure for producing ischemic changes.
متن کاملCerebral Blood Flow in the Four-Vessel Occlusion Rat Model
are most likely a result of MCA occlusion. For most old rats, the thicker skull requires more drilling, and connective tissue about the vessel presents more resistance to dissection of the MCA making hemorrhage more likely than in younger rats. While the smaller lesions in older rats (734-852) are larger (p < 0.05) than for the younger rats (752-842), the size difference may be due to more surg...
متن کاملCerebral blood flow in the four-vessel occlusion rat model.
are most likely a result of MCA occlusion. For most old rats, the thicker skull requires more drilling, and connective tissue about the vessel presents more resistance to dissection of the MCA making hemorrhage more likely than in younger rats. While the smaller lesions in older rats (734-852) are larger (p < 0.05) than for the younger rats (752-842), the size difference may be due to more surg...
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Four-vessel occlusion in rats was introduced approximately 10 years ago to provide a rodent model of reversible forebrain ischemia. The model presented several advantages, which included ease of preparation, a high rate of predictable ischemic neuronal damage, a low incidence of seizures, and the absence of anesthesia. However, two issues concerning the efficient use of the four-vessel occlusio...
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BACKGROUND AND PURPOSE We introduce the concept of a switching strategy for mechanical thrombectomy with period-to-period analysis. In period 1, forced arterial suction thrombectomy with a Penumbra reperfusion catheter was performed, even in difficult cases; in period 2, forced arterial suction thrombectomy was initially performed, with switching to Solitaire in difficult cases. METHODS We an...
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ژورنال
عنوان ژورنال: Stroke
سال: 2005
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.0000182238.08510.c5